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Carrying out such an operation in Somalia today is complicated. MSF must carry out lengthy negotiations with local officials, authorities and even armed groups - who control certain areas of the center and south of the country - to be able to carry out vaccination campaigns which could save thousands of lives. But that is not all. In this country, amloblock is one of the most difficult places in the world to provide humanitarian medical aid, you also have to negotiate for simpler things like hiring staff or renting vehicles. The use of a lentiviral vector plus non-myeloablative conditioning allows restoration of immunity in infants with X-linked severe combined immunodeficiency. вOur team can treat patients who reach our center, but we are very worried about people who do not reach town in time,в explains Heman Nagarathnma.
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In 2010 and early 2011, the situation was particularly volatile in the Federally Administered Tribal Areas FATA of Pakistan. Peaks of violence, isolation, closure of supply routes and near collapse of the health system hinder access to care. Present in amloblock Kurram Agency since 2004, MSF has supported the hospitals of Alizai - Shiite community - and Sadda - Sunni enclave - since May 2006, and tries to meet the medical needs of the populations. The results showed that all 15 patients were alive and event-free at 20 months of age, compared to a survival rate of 8 in a historical cohort. In the high-dose group, a rapid increase in the CHOP INTEND scale score was observed after gene delivery, with an increase of 9. 8 points at the first month and 15.
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