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This study carried out at the Center for Digestive Diseases at the University of Nottingham, in the United Kingdom, hypothesizes that polymorphisms in genes whose expression is altered by gastroenteritis may be related to IBS and diarrhea IBS-D, which which closely resembles post-infectious irritable bowel syndrome PI-IBS. The methodology proposed two phases. Part 1 25 healthy volunteers VS, 21 patients 6 months after Campylobacter jejuni infection, 37 with IBS-D and 19 with IBS plus constipation Anzo underwent rectal biopsy for gene expression analysis and evaluation of cytokine production of mononuclear cells from peripheral blood.

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