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Cardiologists from the Valencia General University Hospital Consortium, Valencia, Spain, evaluated the predictive value of blood levels of PGC-1О in the extension of the necrotic area and ventricular remodeling after infarction. The prospective study considered 31 patients with first myocardial infarction of anterior location and successful reperfusion. The expression of PGC-1О was determined in peripheral blood upon admission and at 72 hours, evaluating its correlation with myocardial damage and ventricular volume and systolic function at 6 months.
Myocardial edema and necrosis were estimated by cardiac MRI during the first week. At 6 months, a control MRI evaluated infarct size and ventricular remodeling, defined as 10 increase in left ventricular end-diastolic volume. Saved myocardium was defined as the difference between the areas of edema and necrosis. In the middle of all this, I organize small meetings with the referring doctor and the logistician to on the one hand check that everything is in place в for example that the ambulances are available в and on the other hand to cross-check our information and whether other victims are expected among other things. According to our assessments in the sector, the most urgent needs of the population are drinking water, food and medical aid.
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