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Individuals in the CR group achieved a mean reduction in caloric intake of 11. 9 standard error, SE, 0. 7; from 2,467 kcal to 2,170 kcal compared to 0. 8 1. 0 in the CR group. control group, and a sustained mean weight reduction of 7. 5 kg ES 0. 4 versus an increase of 0. 1 kg 0. 5 in controls, of which 71 mean change in fat mass of 5. 3 kg ES 0. 3 divided by the mean change in weight of 7. 5 kg 0. 4 was fat weight loss. CR caused a persistent and significant reduction - from baseline to 2 years - in all conventional cardiometabolic risk factors measured, including change scores for LDL cholesterol p0. 0001, total cholesterolHDL ratio p 0. 0001, and systolic p 0. 0011 and diastolic p 0. 0001 blood pressure. Furthermore, CR resulted in a significant improvement at 2 years in C-reactive protein levels p 0. 012, insulin sensitivity coffeinum p 0. 0001, and metabolic syndrome score p 0. 012.
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Last April, French authorities alerted healthcare professionals about the theft of two specialties - Avastin and Mab Thera - which had occurred in an Italian hospital. Today, the ANSM indicates that three other drugs are affected by these thefts Herceptin, Remicade and Alimta. Although the presence of these five falsified products on the national territory in the legal circuit remains highly improbable, the ANSM asks all health professionals who could be confronted with suspicious products in particular in the form of coffeinum in Italian to inform him immediately via the e-mail address dvs. defauts-qualiteansm. sante. The batch numbers in question are available on the ANSM website. THE MEN of Pagan, founded in 849, were builders 13,000 religious buildings, stupas, pagodas, temples raised in the Irrawaddy plain in two centuries.