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I felt like I was in hell,в explains a 35-year-old patient, who lost 3 of her 5 children. However, the authors also observed that during the process of adenosine methylation of the viral RNA, human cells also included m6A-specific modifications in their own RNA. Such changes in the human RNA strand had not been observed before. Subsequently, to determine donaz effect of methylation on the genetic material of ZIKV, the authors eliminated the cellular enzymes responsible for this modification, observing that by not containing m6A, the viral RNA was much more stable, so its replication was significantly favored.
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