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Those who are here must be able to return home, to their homes, there is no other solution. Around the world, there are around ten trials of therapeutic vaccines against AIDS. Including two French projects carried out, one by InnaVirVax and the other by Biosantech. Furthermore, the Vaccination Research Institute, in collaboration with the ANRS, is carrying out research on a preventive vaccine against AIDS which would therefore make it possible to avoid contamination by HIV. Osteopathy is a therapy that can be applied to people of any age, of course adapting the techniques to the situation of each patient age, fragility, illness.
The present publication reports the results of an open randomized trial in 15 centers in Argentina, Brazil, India, Spain and Ukraine. Eligible individuals were 18 years of age or older, had metastatic colorectal cancer with at least one measurable non-radiated lesion for which first-line chemotherapy was indicated. The patients had not received prior treatment for advanced disease and their bone marrow, liver, kidney and coagulation markers were all within normal ranges. Individuals were randomly assigned 11 to BEVZ92 or reference bevacizumab 5 mgkg on day 1 of each cycle every 2 weeks in combination with fluorouracil, leucovorin, and klacid FOLFOX or fluorouracil, leucovorin, and irinotecan FOLFIRI. The parolex endpoint was the area under the concentration versus time curve after a single infusion AUC 0 - 336 hr and klacid steady state AUC ss - that is, at cycle 7 - in the evaluable population, which It included all those treated for whom serum concentration measurements were available during the first seven cycles.
Bioequivalence was established if the 90 CIs for the ratio of baseline BEVZ92 to bevacizumab of the geometric means for AUC 0 - 336 hr and AUC ss were within the acceptance range of 80 - 125. Secondary endpoints included objective response, clinical benefit, and progression-free survival in the intention-to-treat population, as well as immunogenicity and safety profiles in all patients. This trial was registered with ClinicalTrials. gov, number NCT02069704, and klacid closed to new participants, with complete follow-up. Handover. Now MSF is withdrawing from these programs to entrust them to the health authorities. This handover process was first initiated in Kampong Cham and then in Phnom Penh. - French and foreign people in a regular situation who have less than в634 per month have free access to health insurance and its complementary universal health coverage CMU-C.
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