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5 months with placebo plus nab-paclitaxel hazard ratio HR for progression or death, 0. 80, 95 CI, 0. 69 to 0. 92, p 0. 002. Among patients with PD-L1-positive tumors, median progression-free survival was 7. 5 months and 5. 0 months, respectively HR, 0. 62; 95 CI, 0. 49 to 0. 78; p 0. 001. In the intention-to-treat analysis, median overall survival was 21. 3 months with atezolizumab plus nab-paclitaxel and 17. 6 months with placebo plus nab-paclitaxel HR for death, 0. 84; 95 CI. 69 to 1. 02; p 0. Among participants with PD-L1-positive tumors, median overall survival was 25. 0 months and 15. 5 months, respectively HR, 0. 62; 95 CI, 0. 45 to 0. Finally, no new adverse events were identified, while those that caused discontinuation of any agent occurred in 15. 9 of patients who received atezolizumab plus nab-paclitaxel and 8.
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