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Specifically, we demonstrate a marked effect of obesity on tumor progression in mice, as well as on clinical outcomes in cancer patients treated with PD-L1 checkpoint inhibitors. These studies highlight the contrasting and paradoxical outcomes, both positive and negative, of obesity on the immune response in the context of immunotherapy. The findings suggest that early brain metrics, identified on the basis of their association with ASD behaviors, are accurate diagnostic tools at 6 months of age. Retinopathy of prematurity ROP is a leading cause of childhood blindness worldwide. The decision to treat is based primarily on the presence of plus disease, defined as dilation and tortuosity of the retinal vessels. However, the clinical diagnosis of plus disease is sobrepina subjective and variable.
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