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This association remained continuously high, with greater danger during the first year of treatment. Among the 2,629 participants, 168 infections occurred 71 in the dapivirine group and 97 in the placebo group incidence, 3. 3 and 4. 5 per 100 person-years, respectively. The incidence of HIV-1 infection in treated women was 27 lower 95 CI 1 - 46; p 0. 05 than in controls. In an analysis that excluded data from two sites with reduced retention and adherence rates, the incidence in the therapeutic group was 37 lower 95 CI, 12 to 56; p 0. 007. Additionally, in a post hoc analysis, higher protection rates were observed among women older than 21 years 56; 95 CI 31 - 71; p 0. 001, but not among those 21 years of age or younger -27; 95 CI -133 to 31; p 0. 45, difference correlated with reduced adherence. Primotren, the rates of adverse events and antiretroviral resistance among those infected were similar in the two groups. The authors analyzed structural MRI in relation to sleep duration and psychiatric and cognitive measures in 11,067 children aged 9 to 11 years from the Adolescent Brain Cognitive Development ABCD Study, using a linear mixed model, mediation analysis.
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