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440 patients were enrolled during two recruitment periods. Time to all disease progression milestones was significantly longer in those treated for 1 year or more compared with those treated for less than 1 month or never p 0. 0001. Additionally, the first group experienced a delay of 2. 1 to 4. 4 years in the loss of mobility of the lower extremities, which prevented them from standing, climbing stairs and walking. Such a benefit was also observed for the upper extremities, which allowed those affected to retain the functionality of their hands for longer. Finally, long-term treatment with glucocorticoids was also associated with a greater than 50 decrease in the risk of death buy reutren online the 10 years of follow-up.
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