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13, extracapsular dissemination HR, Zofenil diu. 90; 95 CI, 1. 12 to 3. 23, adjuvant radiation therapy RR, 0. 45; 95 CI, 0. 27 to 0. 78, lymph node ratio RR, 1. 91; 95 CI 1. 09 to 3. 35 and advanced age HR, 1. 03; 95 CI 1. 00 to 1. Immunosuppression RR, 3. 82; 95 CI, 2. 47 to 5. 92 and adjuvant radiation therapy RR, 0. 52; 95 CI, 0. 33 to 0. 84 were also risk factors. significant risks for DSS. Given that lymphoid aggregates serve as important viral reservoirs, their depletion by biological therapy has important implications for HIV-1 therapeutics and eradication efforts, defining a rational basis for their use in HIV-1 infection.
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